| Schedule |
| Time | Sport | Event | National | Away TV | Home TV |
| MLB | Oakland Athletics @ Baltimore Orioles | | Comcast | MASN2 |
| MLB | Los Angeles Angels @ Chicago White Sox
GameCenter | | KCOP | Comcast |
| NFL | Detroit Lions @ Atlanta Falcons
GameCenter | FOX Regional | | |
| NFL | Cincinnati Bengals @ Baltimore Ravens
GameCenter | CBS - HD (Regional) | | |
| NFL | Seattle Seahawks @ Buffalo Bills
GameCenter | FOX Regional | | |
| NFL | New York Jets @ Miami Dolphins
GameCenter | CBS - HD (Regional) | | |
| NFL | Kansas City Chiefs @ New England Patriots
GameCenter | CBS - HD (Regional) | | |
| NFL | Tampa Bay Buccaneers @ New Orleans Saints
GameCenter | FOX Regional | | |
| NFL | St. Louis Rams @ Philadelphia Eagles
GameCenter | FOX Regional | | |
| NFL | Houston Texans @ Pittsburgh Steelers
GameCenter | CBS - HD (Regional) | | |
| NFL | Jacksonville Jaguars @ Tennessee Titans
GameCenter | CBS - HD (Regional) | | |
| Tennis | 2008 US Open-Women's Doubles Final | USA Network | | |
| MLB | Tampa Bay Rays @ Toronto Blue Jays
GameCenter | | FSN Regional | |
| MLB | Philadelphia Phillies @ New York Mets
GameCenter | | WPSG | SNY |
| MLB | Chicago Cubs @ Cincinnati Reds
GameCenter | | WGN | |
| MLB | Washington Nationals @ Atlanta Braves
GameCenter | | MASN | SportSouth |
| MLB | San Diego Padres @ Milwaukee Brewers
GameCenter | | Ch. 4 Padres | FSN Regional |
| MLB | Cleveland Indians @ Kansas City Royals
GameCenter | | STO Network | |
| MLB | Detroit Tigers @ Minnesota Twins
GameCenter | | FSN Regional | WFTC |
| MLB | Florida Marlins @ St. Louis Cardinals
GameCenter | | Sun Sports | FSN Regional |
| MLB | Boston Red Sox @ Texas Rangers
GameCenter | | NESN | KDFI |
| MLB | Houston Astros @ Colorado Rockies
GameCenter | | | FSN Regional |
| Tennis | 2008 US Open-Men's Semifinal | CBS - HD National | | |
| MLB | Pittsburgh Pirates @ San Francisco Giants
GameCenter | | | Comcast |
| MLB | Arizona Diamondbacks @ Los Angeles Dodgers
GameCenter | | FSN Regional | FSN Regional |
| MLB | New York Yankees @ Seattle Mariners
GameCenter | | YES Network | FSN Regional |
| NFL | Dallas Cowboys @ Cleveland Browns
GameCenter | FOX Regional | | |
| NFL | Carolina Panthers @ San Diego Chargers
GameCenter | FOX Regional | | |
| NFL | Arizona Cardinals @ San Francisco 49ers
GameCenter | FOX Regional | | |
| NFL | Chicago Bears @ Indianapolis Colts
GameCenter | NBC | | |
| Tennis | 2008 US Open-Women's Final | CBS - HD National | | |
